Measurement

Reproducibility

Definition

The closeness of agreement between independent measurement results obtained under changed conditions, such as different operators, instruments, laboratories, or time periods.

Explanation

A mass spectrometry method is reproducible if three different laboratories analyzing the same blood sample all report a glucose concentration within 2% of each other. Reproducibility is broader than repeatability (same conditions): a weight measured to ±0.01 g by the same operator on the same day may have reproducibility of only ±0.05 g across laboratories due to instrument-to-instrument variation.

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